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J Chromatogr B 871:328340 Sun J, Schnackenberg LK, Beger RD (2009) Studies of acetaminophen and metabolites in urine and their correlations with toxicity using metabolomics
Furthermore, it is well-established that many of these species can give rise to secondary oxidants with different reactivity and lifespan than the initial ones (reviewed in Halliwell and Gutteridge, 2015)
15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25 Although inflammation is a powerful driver of tumor growth, 26 it is the aim of this review to focus on the connection between insulin/IGF-1 signaling and cancer, and discuss possibilities to modulate these interactions through DR and pharmaceutical interventions to improve cancer outcomes