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opioids Mexiletine Lidocaine (IV/topical) Tramadol Morphine (IV) Alfentanil (IV) Ketamine (IV) Methylprednisone (intrathecal) Adenosine Glycine antagonist Desipramine Venlafaxine Pregabalin Static mechanical allodynia sodium channel blockers, opioids Lidocaine (IV) Alfentanil (IV) Adenosine (IV) Ketamine (IV) Glycine antagonist Venlafaxine Gabapentin (may also be helpful in cold and dynamic allodynias) Cold allodynia Lamotrigine Lidocaine (IV) The list of compounds that can be used to treat allodynia is even longer than this

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If you need it, especially for a persistent headache, over-the-counter pain relievers like ibuprofen or acetaminophen can help

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