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In a phase 2 clinical trial, retatrutide reduced HbA1c to 2.02%, compared to 1.41% for dulaglutide 1.5 mg and 0.01% for placebo (Table 1)
You can certainly combine the shots in the same syringe, but I do not recommend it (unless you are an expert), because if you get an air bubble in the syringe, as you extract the liquid from the vial, you will need to slowly return the liquid into the vial and re-extract it again till theres no bubbles
[Carrington, Lila] on Amazon.com
Some preliminary work in this area exists
There's no universally established optimal concentration
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