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All AEs were mild or moderate in severity

In the study, participants with a responsive genetic score had an 82% increase in the likelihood of acheiving weight loss with a GLP-1 medication.[ref] Another study showed that GLP1 receptor variants are associated with greater weight loss on GLP-1 RA drugs.[ref] Common genetic variants in the GLP1R (GLP-1 receptor) gene impact weight and type 2 diabetes risk

Patients who are actively trying to conceive or planning pregnancy within the next few months should discuss whether initiating semaglutide is appropriate, given the FDA recommendation to discontinue the medication at least 2 months before planned conception

Nutricion Hospitalaria, 36(6), 14241429