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Available from: Accessed 28 June 2025 Medicines and Healthcare products Regulatory Agency
There was a significant reduction in the risk of CRC in patients who received GLP-1RAs when compared with all other antidiabetic medications, except alpha-glucosidase or DPP-4i, in which there was a non-significant reduced risk
To summarize, the present results showed that Ex-4 influences the expression of genes related to mitochondrial biogenesis, energy expenditure, and mitochondrial uncoupling, including FNDC5 coding for irisin, as well as mildly stimulating mitochondrial activity
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