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For weight management, it is approved for adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity, as an adjunct to a reduced-calorie diet and increased physical activity

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[46], corroborated this finding by showing that the addition of a GST inhibitor (diethyl maleate) led to reduced LC 50 levels in resistant ticks (Shakya et al