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In a study conducted on allergic asthmatic mice it has been demonstrated that prenatal but not postnatal exposure to tobacco smoke exacerbates airway reactivity, strongly upregulates allergen-induced Th2 cytokine expression, and increases total serum IgE levels [78]

(OR 0.37, 95% CI, 0.16-0.86)

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Additionally, the demand for tobacco products was just as responsive to changes in price in lower-income countries as it was in high-income countries

The agency has issued more than 450 warnings over the years to various vaping companies