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This highlights a significant clinical implication, as smoking could undermine the effectiveness of crucial treatments aimed at eradicating the virus and preventing disease progression

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In a randomized crossover trial comparing healthy subjects who smoked tobacco (maximum of 10 cigarettes per month), the acute use of nicotine-containing e-cigarettes significantly increased levels of circulating endothelial progenitor cells (flow cytometry) to the same magnitude as after smoking a traditional cigarette (41)