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Once that dopamine rush wears off, you begin to crave nicotine, says Panagis Galiatsatos, MD, the director of the Tobacco Treatment Clinic at Johns Hopkins Medicine
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Nutritional risk factors in esophageal cancer
Chemical dependence: Nicotine creates dopamine spikes, making your brain dependent on external stimulation instead of natural reward cycles
The problem with that assertion is that up to half the nicotine used in these products may still be derived from tobacco plants
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