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We also monitored the translocation of NF-B p65, the major DNA-binding subunit of the NF-B protein into the nucleus, after treatment with NF-B inhibitors, IKK-16 (Fig

Since the liver is the main organ responsible for arsenic metabolism, and it is exposed to higher arsenic concentrations through the portal circulation which transports the arsenic ingested ( Additionally, in Wistar rats exposed to arsenic (3 ppm) in utero and during early life, developed alteration in the levels of triglycerides, lysophospholipids and phosphatidylcholines (120)

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