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Details Category: Smoking Object Number: 2000-32 Materials: plastic (unidentified), cardboard, paper (fibre product) and dried tobacco Measurements: overall: 85 mm x 50 mm x 20 mm, type: cigarettes credit: Harrods Limited

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INTRODUCTION Nicotine dependence is recognized as a chronic non-communicable disease 1 , associated with many other diseases with high morbidity and mortality 2

Patient-derived xenograft (PDX) cell lines NB-PDX2 and NB-PDX3 (termed LU-NB-2 and LU-NB-3 in previous publications) were cultured as described on LN-521 (Biolamina) coated primaria plates (VWR) in defined, bFGF/EGF supplemented medium 56,57