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While this directive represents an important step, it must be complemented by broader regulations, including advertising bans, flavour restrictions, and indoor-use prohibitions, applied consistently across all nicotine products

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Tar retention relative to other biomarkers in cigarette smokers switching to products with lower tar yields

In terms of DALYs lost from smoking, GBD projections show a decline in rate (DALYs per 100,000 people) but projects that the aggregate number of DALYs will increase in some regions as their populations grow