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Among men, the pooled relative risk for coronary heart disease was 1.48 for smoking one cigarette per day and 2.04 for 20 cigarettes per day, using all studies, but 1.74 and 2.27 among studies in which the relative risk had been adjusted for multiple confounders
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Some states tax based on manufacturer, wholesale, or retail price ( ad valorem ), while other states tax based on product volume or number of cartridges ( ad quantum )
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