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Longitudinal Association of Tobacco Product Use with Health-Related Quality of Life From Waves 1-5 Reference Group: P30D Exclusive Cigarette Use: When evaluating the longitudinal relationship between tobacco product use and change in PROMIS scores over the four 2-wave pairs, cigarette and e-cigarette dual use at baseline wave was associated with worsening overall health over time (beta=-0.08, CI [-0.16, -0.01]) compared to exclusive cigarette use

Initially, the leaves were simply picked and piled in heaps to dry but methods gradually advanced over time and it was discovered that tobacco cured better when hung

60 th Tobacco Science Research Conference, Montreal, Canada, Paper 76 Acknowledgements The authors thank Dr B